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Article

Nature vs nurture in knee osteoarthritis - the importance of age, sex and body mass index.

Osteoarthritis and cartilage - 1 Apr 2019

Magnusson K, Turkiewicz A, Englund M

Abstract excerpt

OBJECTIVE: (1) To estimate the life-time genetic contribution for knee osteoarthritis (OA) surgery and (2) to explore any differences in the genetic contribution across age, sex and body mass index (BMI). METHODS: We studied the sex-specific genetic contribution to knee OA surgery in a prospective cohort study of 62,490 twins aged 35 years or older with a follow-up period of up to 47 years (10,092 identical and...

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PMID: 30634033
DOI: 10.1016/j.joca.2018.12.018

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