Article
The genetic contribution to longitudinal changes in knee structure and muscle strength: a sibpair study.
Arthritis and rheumatism - 1 Sept 2005
Zhai Guangju, Ding Changhai, Stankovich James, Cicuttini Flavia, Jones Graeme
Abstract excerpt
OBJECTIVE: To estimate the heritability of longitudinal changes in knee cartilage volume, chondral defects, subchondral bone size, and lower limb muscle strength. METHODS: A sibpair design was used. Longitudinal changes in lateral and medial tibial cartilage volume and bone size, as well as progression of chondral defects, were determined on serial magnetic resonance images. Radiographs were obtained and scored...
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