Relative risk of knee chondrocalcinosis in siblings of index cases with pyrophosphate arthropathy.

doi:10.1136/ard.2003.015206

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Article

Relative risk of knee chondrocalcinosis in siblings of index cases with pyrophosphate arthropathy.

Annals of the rheumatic diseases - 1 Aug 2004

Zhang W, Neame R, Doherty S, Doherty M

Abstract excerpt

OBJECTIVES: To examine the genetic contribution to common, apparently sporadic, radiographic knee chondrocalcinosis (CC) and pyrophosphate arthropathy (PA). METHOD: (1). DESIGN: radiographic sibling study. Comparison of the prevalences of knee CC and PA in siblings of index cases with PA with those in the community. (2). SUBJECTS: 80 index cases with PA listed for total knee replacement; 122 of their siblings...

Topics

Adult
Aged
Chondrocalcinosis
England
Female
Genetic Predisposition to Disease
Humans
Knee Joint
Male
Middle Aged
Odds Ratio
Osteoarthritis, Knee
Prevalence
Risk Factors

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Identifiers

PMID: 15249324
DOI: 10.1136/ard.2003.015206
PMCID: PMC1755084

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