Article
Pathological dynamics of activated microglia following medial forebrain bundle transection.
Glia - 1 Jan 2006
Cho Byung P, Song Dae Y, Sugama Shuei, Shin Dong H, Shimizu Yoshinori, Kim Sung S, Kim Yoon S, Joh Tong H
Abstract excerpt
To elucidate the role and pathological dynamics of activated microglia, this study assessed the phagocytic, immunophenotypic, morphological, and migratory properties of activated microglia in the medial forebrain bundle (MFB) axotomized rat brain. Activated microglia were identified using two different monoclonal antibodies: ED1 for phagocytic activity and OX6 for major histocompatibility complex (MHC) class II....
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