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Article

Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes.

Scientific reports - 2 Dec 2014

Tam Wing Yip, Ma Chi Him Eddie

Abstract excerpt

Microglia are generally considered the resident immune cells in the central nervous system (CNS) that regulate the primary events of neuroinflammatory responses. Microglia also play key roles in repair and neurodegeneration of the CNS after injury. Recent studies showed that trains of bipolar/rod-shaped microglia align end-to-end along the CNS injury site during the initial recovery phase. However, the cellular...

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PMID: 25452009
DOI: 10.1038/srep07279
PMCID: PMC4250916

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