Article
A Brief History of Microglial Ultrastructure: Distinctive Features, Phenotypes, and Functions Discovered Over the Past 60 Years by Electron Microscopy.
Frontiers in immunology - 1 Jan 2018
Savage Julie C, Picard Katherine, González-Ibáñez Fernando, Tremblay Marie-Ève
Abstract excerpt
The first electron microscope was constructed in 1931. Several decades later, techniques were developed to allow the first ultrastructural analysis of microglia by transmission electron microscopy (EM). In the 50 years that followed, important roles of microglia have been identified, specifically due to the ultrastructural resolution currently available only with EM. In particular, the addition of electron-dense...
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