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Article

Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke.

Glia - 1 Jun 2009

Thored Pär, Heldmann Ursula, Gomes-Leal Walace, Gisler Ramiro, Darsalia Vladimer, Taneera Jalal, Nygren Jens M, Jacobsen Sten-Eirik W, Ekdahl Christine T, Kokaia Zaal, Lindvall Olle

Abstract excerpt

Neural stem cells (NSCs) in the adult rat subventricular zone (SVZ) generate new striatal neurons during several months after ischemic stroke. Whether the microglial response associated with ischemic injury extends into SVZ and influences neuroblast production is unknown. Here, we demonstrate increased numbers of activated microglia in ipsilateral SVZ concomitant with neuroblast migration into the striatum at 2,...

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PMID: 19053043
DOI: 10.1002/glia.20810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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