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Article

Phosphorylation site mutated RB exerts contrasting effects on apoptotic response to different stimuli.

Oncogene - 2 Mar 2006

Masselli A, Wang J Y J

Abstract excerpt

The retinoblastoma tumor-suppressor protein (RB) is an important regulator of cell cycle and apoptosis. RB is phosphorylated by cyclin-dependent protein kinase during cell cycle progression. A phosphorylation site mutated (PSM)-RB has previously been shown to cause G1 arrest and to interfere with S phase progression. In this study, we examined the effect of inducible PSM-RB expression on the apoptotic response to...

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Source

Identifiers

PMID: 16205627
DOI: 10.1038/sj.onc.1209161

Genes

STS
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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