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Article

Evidence for serpinB2-independent protection from TNF-alpha-induced apoptosis.

Experimental cell research - 1 Feb 2006

Fish Richard J, Kruithof Egbert K O

Abstract excerpt

Clade B serine proteinase inhibitors (serpins) are intracellular proteins, whereas most of their identified targets are extracellular. A proposed intracellular role for these inhibitors is protection from apoptosis. We investigated the contribution of serpinB2 (plasminogen activator inhibitor-2, PAI-2) activity in TNF-alpha-induced apoptosis. PAI-2 is expressed in many normal and transformed cell types,...

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Identifiers

PMID: 16330024
DOI: 10.1016/j.yexcr.2005.11.003

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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