Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common polymorphisms in the USF1 gene are not associated with type 2 diabetes in French Caucasians.

Diabetes - 1 Oct 2005

Gibson Fernando, Hercberg Serge, Froguel Philippe

Abstract excerpt

Upstream transcription factor 1 (USF1) is a ubiquitously expressed transcription factor of the basic helix-loop-helix leucine zipper family that has been shown to regulate the expression of a raft of key genes involved in glucose and lipid metabolism. The USF1 gene is located at chromosome 1q22-q23, within the most consistently replicated type 2 diabetes susceptibility locus in the human genome. In this study, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Body Mass Index
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to France

Share to Lipids

Share to Upstream Stimulatory Factors

Share to White People

Source

Identifiers

PMID: 16186412
DOI: 10.2337/diabetes.54.10.3040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common polymorphisms in the USF1 gene are not associated with type 2 diabetes in French Caucasians.PMID 16186412Read ↗

Genetic variants in the USF1 gene are associated with low-density lipoprotein cholesterol levels and incident type 2 diabetes mellitus in women: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.Semantic proximity Read ↗

Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.Semantic proximity Read ↗

Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: association study in 2000 Dutch Caucasians.Semantic proximity Read ↗

Variation in USF1 shows haplotype effects, gene : gene and gene : environment associations with glucose and lipid parameters in the European Atherosclerosis Research Study II.Semantic proximity Read ↗

Functional variant disrupts insulin induction of USF1: mechanism for USF1-associated dyslipidemias.Semantic proximity Read ↗

USF1 and dyslipidemias: converging evidence for a functional intronic variant.Semantic proximity Read ↗

Risk alleles of USF1 gene predict cardiovascular disease of women in two prospective studies.Semantic proximity Read ↗

USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease.Semantic proximity Read ↗

The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population.Semantic proximity Read ↗

Lack of association between genetic polymorphisms within DUSP12 - ATF6 locus and glucose metabolism related traits in a Chinese population.Semantic proximity Read ↗

USF1 gene variants, cardiovascular risk, and mortality in European Americans: analysis of two US cohort studies.Semantic proximity Read ↗

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.