Article
Lack of association between genetic polymorphisms within DUSP12 - ATF6 locus and glucose metabolism related traits in a Chinese population.
BMC medical genetics - 6 Jan 2011
Hu Cheng, Zhang Rong, Wang Congrong, Ma Xiaojing, Wang Jie, Bao Yuqian, Xiang Kunsan, Jia Weiping
Abstract excerpt
BACKGROUND: Genome-wide linkage studies in multiple ethnic populations found chromosome 1q21-q25 was the strongest and most replicable linkage signal in the human chromosome. Studies in Pima Indian, Caucasians and African Americans identified several SNPs in DUSP12 and ATF6, located in chromosome 1q21-q23, were associated with type 2 diabetes. METHODS: We selected 19 single nucleotide polymorphisms (SNPs) that...
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