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Article

The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population.

Diabetologia - 1 Oct 2005

Ng M C Y, Miyake K, So W Y, Poon E W M, Lam V K L, Li J K Y, Cox N J, Bell G I, Chan J C N

Abstract excerpt

AIMS/HYPOTHESIS: The transcription factor upstream stimulatory factor 1 (USF1) regulates the expression of genes involved in glucose and lipid metabolism and has been associated with familial combined hyperlipidaemia. USF1 is located on chromosome 1q22-23, a region with evidence for linkage to type 2 diabetes and various traits of the metabolic syndrome in Chinese and other populations. The aim of this study was...

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Source

Identifiers

PMID: 16132950
DOI: 10.1007/s00125-005-1914-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population.PMID 16132950Read ↗

Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.Semantic proximity Read ↗

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Upstream stimulatory factor 1 associated with familial combined hyperlipidemia, LDL cholesterol, and triglycerides.Semantic proximity Read ↗

Variation in USF1 shows haplotype effects, gene : gene and gene : environment associations with glucose and lipid parameters in the European Atherosclerosis Research Study II.Semantic proximity Read ↗

Genetic variants in the USF1 gene are associated with low-density lipoprotein cholesterol levels and incident type 2 diabetes mellitus in women: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002.Semantic proximity Read ↗

Potential role of upstream stimulatory factor 1 gene variant in familial combined hyperlipidemia and related disorders.Semantic proximity Read ↗

Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1.Semantic proximity Read ↗

Common polymorphisms in the USF1 gene are not associated with type 2 diabetes in French Caucasians.Semantic proximity Read ↗

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).Semantic proximity Read ↗

USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease.Semantic proximity Read ↗

Body mass index is associated with USF1 haplotype in Korean premenopausal women.Semantic proximity Read ↗

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