Article
Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.
Diabetes - 1 Sept 2006
Zeggini Eleftheria, Damcott Coleen M, Hanson Robert L, Karim Mohammad A, Rayner N William, Groves Christopher J, Baier Leslie J, Hale Terri C, Hattersley Andrew T, Hitman Graham A, Hunt Sarah E, Knowler William C, Mitchell Braxton D, Ng Maggie C Y, O'Connell Jeffrey R, Pollin Toni I, Vaxillaire Martine, Walker Mark, Wang Xiaoqin, Whittaker Pamela, Xiang Kunsan, Kunsun Xiang, Jia Weiping, Chan Juliana C N, Froguel Philippe, Deloukas Panos, Shuldiner Alan R, Elbein Steven C, McCarthy Mark I
Abstract excerpt
The gene encoding the transcription factor upstream stimulatory factor (USF)1 influences susceptibility to familial combined hyperlipidemia (FCHL) and triglyceride levels. Phenotypic overlap between FCHL and type 2 diabetes makes USF1 a compelling positional candidate for the widely replicated ty...
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