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Article

Identification of mutations from phenotype-driven ENU mutagenesis in mouse chromosome 7.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2005

Culiat Cymbeline T, Klebig Mitchell L, Liu Zhaowei, Monroe Heidi, Stanford Beverly, Desai Jayashree, Tandan Samvit, Hughes Lori, Kerley Marilyn K, Carpenter Donald A, Johnson Dabney K, Rinchik Eugene M, Li Qingbo

Abstract excerpt

We have used the new high-throughput mutation-scanning technique temperature-gradient capillary electrophoresis (TGCE) for the identification of point mutations induced by N-ethyl-N-nitrosourea (ENU) in the mouse genome. TGCE detects the presence of heteroduplex molecules formed between a wild-type gene segment and the corresponding homologous segment containing an induced mutation or a naturally occurring single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16180137
DOI: 10.1007/s00335-005-0032-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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