Article
The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development.
Cell - 26 Jun 1992
Furukawa T, Maruyama S, Kawaichi M, Honjo T
Abstract excerpt
The J kappa RBP binds to the immunoglobulin recombination signal sequence flanking the kappa-type J segment. We previously isolated the highly conserved homolog of the J kappa RBP gene from D. melanogaster, which is not thought to have immunoglobulin molecules. Using many deficiency mutants and in situ hybridization, we mapped the Drosophila J kappa RBP gene in a region containing two recessive lethal mutations,...
Topics
- Alleles
- Animals
- Base Sequence
- Chromosome Mapping
- Drosophila melanogaster
- Gene Rearrangement
- Molecular Sequence Data
- Morphogenesis
- Peripheral Nerves