Recognition sequence of a highly conserved DNA binding protein RBP-J kappa.

doi:10.1093/nar/22.6.965

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Article

Recognition sequence of a highly conserved DNA binding protein RBP-J kappa.

Nucleic acids research - 25 Mar 1994

Tun T, Hamaguchi Y, Matsunami N, Furukawa T, Honjo T, Kawaichi M

Abstract excerpt

DNA binding specificity of the RBP-J kappa protein was extensively examined. The mouse RBP-J kappa protein was originally isolated as a nuclear protein binding to the J kappa type V(D)J recombination signal sequence which consisted of the conserved heptamer (CACTGTG) and nonamer (GGTTTTTGT) sequences separated by a 23-base pair spacer. Electrophoretic mobility shift assay using DNA probes with mutations in...

Topics

Animals
Base Sequence
Binding Sites
Cell Line
Consensus Sequence
DNA
DNA Probes
DNA Restriction Enzymes
DNA, Recombinant
DNA-Binding Proteins
Drosophila
Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin J Recombination Signal Sequence-Binding Protein

Mice

Molecular Sequence Data

Mutation

Nuclear Proteins

Point Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 8152928
DOI: 10.1093/nar/22.6.965
PMCID: PMC307916

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8152928-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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