Article
Recognition sequence of a highly conserved DNA binding protein RBP-J kappa.
Nucleic acids research - 25 Mar 1994
Tun T, Hamaguchi Y, Matsunami N, Furukawa T, Honjo T, Kawaichi M
Abstract excerpt
DNA binding specificity of the RBP-J kappa protein was extensively examined. The mouse RBP-J kappa protein was originally isolated as a nuclear protein binding to the J kappa type V(D)J recombination signal sequence which consisted of the conserved heptamer (CACTGTG) and nonamer (GGTTTTTGT) sequences separated by a 23-base pair spacer. Electrophoretic mobility shift assay using DNA probes with mutations in...
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