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Article

Mutations at the 3' splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast.

Cell - 26 Jun 1992

Reich C I, VanHoy R W, Porter G L, Wise J A

Abstract excerpt

U1 snRNA is an essential splicing factor known to base pair with 5' splice sites of premessenger RNAs. We demonstrate that pairing between the universally conserved CU just downstream from the 5' junction interaction region and the 3' splice site AG contributes to efficient splicing of Schizosaccharomyces pombe introns that typify the AG-dependent class described in mammals. Strains carrying mutations in the 3'...

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Identifiers

PMID: 1617727
DOI: 10.1016/0092-8674(92)90637-r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations at the 3' splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast.PMID 1617727Read ↗

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