Mutations at the 3' splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast.

doi:10.1016/0092-8674(92)90637-r

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Article

Mutations at the 3' splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast.

Cell - 26 Jun 1992

Reich C I, VanHoy R W, Porter G L, Wise J A

Abstract excerpt

U1 snRNA is an essential splicing factor known to base pair with 5' splice sites of premessenger RNAs. We demonstrate that pairing between the universally conserved CU just downstream from the 5' junction interaction region and the 3' splice site AG contributes to efficient splicing of Schizosacc...

Topics

Base Composition
Base Sequence
Molecular Sequence Data
Mutation
RNA Processing, Post-Transcriptional
RNA Splicing
Schizosaccharomyces

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