Article
Interaction between the bone morphogenetic proteins and Ras/MAP-kinase signalling pathways in lung cancer.
British journal of cancer - 17 Oct 2005
Kraunz K S, Nelson H H, Liu M, Wiencke J K, Kelsey K T
Abstract excerpt
Bone morphogenetic proteins (BMPs) are an integral component of the TGFbeta superfamily, responsible for regulation of cell proliferation, differentiation, migration and programmed cell death in a variety of cell types. The BMPs transduce their signals directly through the SMAD family of proteins but they also have been reported to interact with the MAPK and Erk pathways. Inactivation of the BMP pathway genes has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.