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Article

BALB/c alleles at modifier loci increase the severity of the maternal effect of the "DDK syndrome".

Genetics - 1 Feb 2000

Le Bras S, Cohen-Tannoudji M, Kress C, Vandormael-Pournin S, Babinet C, Baldacci P

Abstract excerpt

The Om locus was first described in the DDK inbred mouse strain: DDK mice carry a mutation at Om resulting in a parental effect lethality of F(1) embryos. When DDK females are mated with males of other (non-DDK) inbred strains, e.g., BALB/c, they exhibit a low fertility, whereas the reciprocal cross, non-DDK females x DDK males, is fertile (as is the DDK intrastrain cross). The low fertility is due to the death...

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Identifiers

PMID: 10655231
DOI: 10.1093/genetics/154.2.803
PMCID: PMC1460929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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BALB/c alleles at modifier loci increase the severity of the maternal effect of the "DDK syndrome".PMID 10655231Read ↗

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Female mice of DDK strain are fully fertile in the intersubspecific crosses with Mus musculus molossinus and M. m. castaneus.Semantic proximity Read ↗

Transmission-ratio distortion through F1 females at chromosome 11 loci linked to Om in the mouse DDK syndrome.Semantic proximity Read ↗

Epigenetic targeting in the mouse zygote marks DNA for later methylation: a mechanism for maternal effects in development.Semantic proximity Read ↗

The paternal gene of the DDK syndrome maps to the Schlafen gene cluster on mouse chromosome 11.Semantic proximity Read ↗

Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.Semantic proximity Read ↗

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