Article
DNA Methylation in Anal Intraepithelial Lesions and Anal Squamous Cell Carcinoma
15 Sept 2005
Abstract excerpt
PURPOSE: Anal intraepithelial neoplasia is associated with human papillomavirus infection and may progress to invasive squamous cell carcinoma (SCC), which is increasing in immunocompromised patients. We hypothesize that anal intraepithelial neoplasia is associated with abnormal DNA methylation and that detection of these events may be used to improve screening programs. EXPERIMENTAL DESIGN: Seventy-six patients...
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