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Article

DNA methylation profiling of cervical squamous intraepithelial lesions using liquid-based cytology specimens

14 Jul 2004

Abstract excerpt

BACKGROUND: Cervical carcinoma is a common malignancy among women worldwide, and its pathogenesis is related causally to human papillomavirus infection. The progression from precursor squamous intraepithelial lesions to cervical carcinoma requires additional genetic and epigenetic alterations that have not been characterized fully. The authors examined aberrant promoter methylation of multiple tumor suppressor...

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Identifiers

PMID: 15368319
DOI: 10.1002/cncr.20425

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