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Article

Promoter Hypermethylation of Tumor Suppressor Genes in Urine from Patients with Cervical Neoplasia

1 Jun 2007

Abstract excerpt

We examined the feasibility of using detection of high-risk human papillomavirus (HPV) DNA in combination with the presence of aberrantly methylated genes (DAPK1, RARB, TWIST1, and CDH13) for urine-based cervical cancer screening. Urine samples from 129 Senegalese women, aged 35 years or older, 110 with (same day) biopsy-proven cervical neoplasia [cervical intraepithelial neoplasia grade 1 (CIN-1): n = 9;...

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PMID: 17548682
DOI: 10.1158/1055-9965.epi-06-0694

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