Article
DNA methylation in human papillomavirus-infected cervical cells is elevated in high-grade squamous intraepithelial lesions and cancer.
Journal of gynecologic oncology - 1 Mar 2016
Kim Mi-Kyung, Lee In-Ho, Lee Ki-Heon, Lee Yoo Kyung, So Kyeong A, Hong Sung Ran, Hwang Chang-Sun, Kee Mee-Kyung, Rhee Jee Eun, Kang Chun, Hur Soo Young, Park Jong Sup, Kim Tae-Jin
Abstract excerpt
OBJECTIVE: DNA methylation has been shown to be a potential biomarker for early cancer detection. The aim of this study was to evaluate DNA methylation profiles according to liquid-based Pap (LBP) test results and to assess their diagnostic value in a Korean population. METHODS: A total of 205 patients with various Papanicolaou test results were enrolled to this study (negative, 26; atypical squamous cells of...
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