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Article

Detection of Hypermethylated Genes in Women with and Without Cervical Neoplasia

15 Feb 2005

Abstract excerpt

BACKGROUND: DNA methylation changes are an early event in carcinogenesis and are often present in the precursor lesions of various cancers. We examined whether DNA methylation changes might be used as markers of cervical intraepithelial neoplasia (CIN) and invasive cervical cancer (ICC). METHODS: We used methylation-specific polymerase chain reaction (PCR) to analyze promoter hypermethylation of 20 genes,...

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Share to Cervical Cancer and HPV Research
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PMID: 15713962
DOI: 10.1093/jnci/dji041

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