The SecY translocation complex: convergence of genetics and structure.

doi:10.1016/j.tim.2007.03.001

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Article

The SecY translocation complex: convergence of genetics and structure.

Trends in microbiology - 1 May 2007

Flower Ann M

Abstract excerpt

All organisms share a requirement for translocation of proteins across membranes. The major mechanism for this process is the universally conserved SecY/Sec61 pathway. Many years of extensive genetic and biochemical analyses identified the components of the SecY/Sec61 pathway, demonstrated that most exported proteins use this route for translocation, and led to understanding of many functions of the components....

Topics

Alleles
Crystallography, X-Ray
Escherichia coli
Escherichia coli Proteins
Models, Biological
Models, Molecular
Protein Structure, Tertiary
Protein Transport
SEC Translocation Channels

Source

Open in PubMed

Identifiers

PMID: 17368028
DOI: 10.1016/j.tim.2007.03.001

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