Article
The SecY translocation complex: convergence of genetics and structure.
Trends in microbiology - 1 May 2007
Flower Ann M
Abstract excerpt
All organisms share a requirement for translocation of proteins across membranes. The major mechanism for this process is the universally conserved SecY/Sec61 pathway. Many years of extensive genetic and biochemical analyses identified the components of the SecY/Sec61 pathway, demonstrated that most exported proteins use this route for translocation, and led to understanding of many functions of the components....
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