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Article

The PrlA and PrlG phenotypes are caused by a loosened association among the translocase SecYEG subunits.

The EMBO journal - 15 Jun 1999

Duong F, Wickner W

Abstract excerpt

prlA mutations in the gene encoding the SecY subunit of the membrane domain of the Escherichia coli preprotein translocase confer many phenotypes: enhanced translocation rates, increased affinity for SecA, diminished requirement for functional leader sequences, reduced proton-motive force (PMF) dependence of preprotein translocation and facilitated translocation of preproteins with folded domains. We now report...

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Identifiers

PMID: 10369667
DOI: 10.1093/emboj/18.12.3263
PMCID: PMC1171407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The PrlA and PrlG phenotypes are caused by a loosened association among the translocase SecYEG subunits.PMID 10369667Read ↗

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A SecE mutation that modulates SecY-SecE translocase assembly, identified as a specific suppressor of SecY defects.Semantic proximity Read ↗

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