Article
The ABC transporter Abcg2/Bcrp: role in hypoxia mediated survival.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine - 1 Aug 2005
Krishnamurthy Partha, Schuetz John D
Abstract excerpt
ABC (ATP-binding cassette) transporters have diverse roles in many cellular processes. These diverse roles require the presence of conserved membrane spanning domains and nucleotide binding domains. Bcrp (Abcg2) is a member of the ATP binding cassette family of plasma membrane transporters that was originally discovered for its ability to confer drug resistance in tumor cells. Subsequent studies showed Bcrp...
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