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Article

Human ABC transporter ABCG2 in cancer chemotherapy and pharmacogenomics.

Journal of experimental therapeutics & oncology - 1 Jan 2009

Ishikawa Toshihisa, Nakagawa Hiroshi

Abstract excerpt

The ability of cancer cells to acquire resistance to multiple anticancer agents, termed multidrug resistance, is often mediated by overexpression of ATP-binding cassette (ABC) transporters that remove drugs out of the cell against a concentration gradient. ABCG2, or breast cancer resistance protein (BCRP), is an ABC transporter that has been the subject of intense study since its discovery a decade ago. While...

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Identifiers

PMID: 19827267

Genes

ABCG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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