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Article

Calcium oscillations and mammalian egg activation

9 Sept 2005

Abstract excerpt

Fertilization in all species studied to date induces an increase in the intracellular concentration of free calcium ions ([Ca2+]i) within the egg. In mammals, this [Ca2+]i signal is delivered in the form of long-lasting [Ca2+]i oscillations that begin shortly after fusion of the gametes and persist beyond the time of completion of meiosis. While not fully elucidated, recent evidence supports the notion that the...

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PMID: 16155907
DOI: 10.1002/jcp.20471

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