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Article

A novel signalling mechanism for generating ca2+ oscillations at fertilization in mammals

1 May 1997

Abstract excerpt

At fertilization in mammals the sperm activates the egg by triggering a series of oscillations in the intracellular free Ca2+ concentration. The precise sequence of events that occur between sperm-egg contact and the increases in intracellular Ca2+ remains unknown. Here, we discuss recent evidence supporting the hypothesis that a cytosolic sperm protein enters the egg after gamete membrane fusion and triggers...

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PMID: 9174402
DOI: 10.1002/bies.950190504

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