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Molecular Mechanism of Oocyte Activation in Mammals: Past, Present, and Future Directions

17 Mar 2024

Abstract excerpt

During mammalian fertilization, repetitive intracellular Ca2+ increases known as Ca2+ oscillations occur. These oscillations are considered crucial for successful fertilization and subsequent embryonic development. Numerous researchers have endeavored to elucidate the factors responsible for inducing Ca2+ oscillations across various mammalian species. Notably, sperm-specific phospholipase C zeta (PLCζ) emerged as...

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PMID: 38540777
DOI: 10.3390/biom14030359

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