Back to search

Article

PLCζ, a sperm-specific PLC and its potential role in fertilization

2007-01-12

Abstract excerpt

A dramatic rise in intracellular calcium plays a vital role at the moment of fertilization, eliciting the resumption of meiosis and the initiation of embryo development. In mammals, the rise takes the form of oscillations in calcium concentration within the egg, driven by an elevation in inositol trisphosphate. The causative agent of these oscillations is proposed to be a recently described phosphoinositide-specif...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
48af155d-e52a-550c-827c-6e10f9abb529
DOI
10.1042/bss2007c03
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
PLCζ, a sperm-specific PLC and its potential role in fertilizationDOI 10.1042/bss2007c03
The role and mechanism of action of sperm PLC-zeta in mammalian fertilisationSemantic proximity
Novel signalling mechanism and clinical applications of sperm-specific PLCζSemantic proximity
The sperm phospholipase C-ζ and Ca2+ signalling at fertilization in mammalsSemantic proximity
Sperm PLCζ: From structure to Ca<sup>2+</sup> oscillations, egg activation and therapeutic potentialSemantic proximity
Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An UpdateSemantic proximity
PLCζ and its role as a trigger of development in vertebratesSemantic proximity
SPERM FACTORS AND EGG ACTIVATION: The structure and function relationship of sperm PLCZ1Semantic proximity
PLCζ(zeta): A sperm protein that triggers Ca2+ oscillations and egg activation in mammalsSemantic proximity
Molecular Mechanism of Oocyte Activation in Mammals: Past, Present, and Future DirectionsSemantic proximity
Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζSemantic proximity
Mammalian Fertilization: From Sperm Factor to Phospholipase CζSemantic proximity
A Novel PLCζ Mutation Linked to Male Factor Infertility Induces a Gain-of-Function Effect on Ca2+ Oscillations in EggsSemantic proximity
Select a neighboring publication to make it the new centre.