Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

INTRACELLULAR CALCIUM IN THE FERTILIZATION AND DEVELOPMENT OF MAMMALIAN EGGS

15 Aug 2007

Abstract excerpt

1. Mammalian eggs are arrested at metaphase of their second meiotic division when ovulated and remain arrested until fertilized. The sperm delivers into the egg phospholipase C (PLC) zeta, which triggers a series of Ca(2+) spikes lasting several hours. The Ca(2+) spikes provide the necessary and sufficient trigger for all the events of fertilization, including exit from metaphase II arrest and extrusion of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microtubule and mitosis dynamics
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17714098
DOI: 10.1111/j.1440-1681.2007.04726.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

INTRACELLULAR CALCIUM IN THE FERTILIZATION AND DEVELOPMENT OF MAMMALIAN EGGSPMID 17714098Read ↗

Molecular triggers of egg activation at fertilization in mammalsSemantic proximity Read ↗

Calcium oscillations and mammalian egg activationSemantic proximity Read ↗

Calcium influx-mediated signaling is required for complete mouse egg activationSemantic proximity Read ↗

Fertilization and early embryology: The role of calcium in mammalian oocyte maturation and egg activationSemantic proximity Read ↗

Regulation of fertilization-initiated [Ca2+]i oscillations in mammalian eggs: A multi-pronged approachSemantic proximity Read ↗

Calcium at Fertilization and in Early DevelopmentSemantic proximity Read ↗

Calcium signaling in mammalian egg activation and embryo development: The influence of subcellular localizationSemantic proximity Read ↗

Spatiotemporal dynamics of intracellular calcium in the mouse egg injected with a spermatozoonSemantic proximity Read ↗

Starting a new life: Sperm PLC‐zeta mobilizes the Ca2+ signal that induces egg activation and embryo developmentSemantic proximity Read ↗

Regulation of the meiotic divisions of mammalian oocytes and eggsSemantic proximity Read ↗

Molecular Mechanism of Oocyte Activation in Mammals: Past, Present, and Future DirectionsSemantic proximity Read ↗

Transitioning from egg to embryo: Triggers and mechanisms of egg activationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.