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Article

Egg activation: Upstream of the fertilization calcium signal

1 Jul 2000

Abstract excerpt

Interaction of sperm and egg at fertilization induces well-coordinated molecular events including specific recognition between species, adhesion and fusion, that lead to the formation of a zygote, a totipotent cell that develops into a new individual. A calcium signal, common to a great number of species, from marine invertebrates to mammals, is essential to activate the metabolism of the unfertilized oocyte....

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PMID: 11043410
DOI: 10.1016/s0248-4900(00)01065-0

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