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Promoter analysis of the rabbit POU5F1 gene and its expression in preimplantation stage embryos

4 Sept 2009

Abstract excerpt

BACKGROUND: The POU5F1 gene encodes the octamer-binding transcription factor-4 (Oct4). It is crucial in the regulation of pluripotency during embryonic development and widely used as molecular marker of embryonic stem cells (ESCs). The objective of this study was to identify and to analyse the promoter region of rabbit POU5F1 gene; furthermore to examine its expression pattern in preimplantation stage rabbit...

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PMID: 19732419
DOI: 10.1186/1471-2199-10-88

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