Article
A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter.
Developmental biology - 15 Jun 2005
Reece-Hoyes John S, Keenan Iain D, Pownall Mary Elizabeth, Isaacs Harry V
Abstract excerpt
Cdx homeodomain transcription factors have multiple roles in early vertebrate development. Furthermore, mis-regulation of Cdx expression has been demonstrated in metaplasias and cancers of the gut epithelium. Given the importance of Cdx genes in development and disease, the mechanisms underlying their expression are of considerable interest. We report an analysis of the upstream regulatory regions from the...
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