Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A far-upstream Oct-1 motif regulates cytokine-induced transcription of the human inducible nitric oxide synthase gene.

Journal of molecular biology - 24 Jul 2009

Park Kyung Soo, Guo Zhong, Shao Lifang, Du Qiang, Geller David A

Abstract excerpt

Transcriptional regulation of the human inducible nitric oxide synthase (hiNOS) gene is highly complex and requires an orchestrated flow of positive and negative transcription factors that bind to specific cis-acting upstream response elements. Very little specific information exists about the far-upstream region of the hiNOS gene. Oct-1 protein belongs to the Pit-Oct-Unc domain transcription factor family and is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Chromatin Immunoprecipitation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Hepatocytes

Share to Nitric Oxide Synthase Type II

Share to Octamer Transcription Factor-1

Share to RNA, Small Interfering

Share to Thymidine Kinase

Source

Open in PubMed Open full text

Identifiers

PMID: 19467240
DOI: 10.1016/j.jmb.2009.05.036
PMCID: PMC2747512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A far-upstream Oct-1 motif regulates cytokine-induced transcription of the human inducible nitric oxide synthase gene.PMID 19467240Read ↗

Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter.Semantic proximity Read ↗

Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene.Semantic proximity Read ↗

Sp1 Regulates Chromatin Looping between an Intronic Enhancer and Distal Promoter of the Human Heme Oxygenase-1 Gene in Renal CellsSemantic proximity Read ↗

Deciphering Pro-angiogenic Transcription Factor Profiles in Hypoxic Human Endothelial Cells by Combined Bioinformatics and in vitro ModelingSemantic proximity Read ↗

Activation of the iNOS gene promoter by Brn-3 POU family transcription factors is dependent upon the octamer motif in the promoter.Semantic proximity Read ↗

Characterization of an Upstream Enhancer Region in the Promoter of the Human Endothelial Nitric-oxide Synthase GeneSemantic proximity Read ↗

Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: The role of NF-κB-repressing factor (NRF) in basal repression of the hiNOS geneSemantic proximity Read ↗

Characterization of putative cis-regulatory elements that control the transcriptional activity of the human Oct4 promoter.Semantic proximity Read ↗

Identification of an octamer element required for in vivo expression of the TIE1 gene in endothelial cells.Semantic proximity Read ↗

Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice.Semantic proximity Read ↗

Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer.Semantic proximity Read ↗

Characterization of the Human Endothelial Nitric-oxide Synthase PromoterSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.