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Article

The histone chaperone Asf1p mediates global chromatin disassembly in vivo.

The Journal of biological chemistry - 10 Dec 2004

Adkins Melissa W, Tyler Jessica K

Abstract excerpt

The packaging of the eukaryotic genome into chromatin is likely to be mediated by chromatin assembly factors, including histone chaperones. We investigated the function of the histone H3/H4 chaperones anti-silencing function 1 (Asf1p) and chromatin assembly factor 1 (CAF-1) in vivo. Analysis of chromatin structure by accessibility to micrococcal nuclease and DNase I digestion demonstrated that the chromatin from...

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Identifiers

PMID: 15452122
DOI: 10.1074/jbc.M406113200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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