Article
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells.
American journal of physiology. Lung cellular and molecular physiology - 1 Feb 2006
Fang Xiaohui, Song Yuanlin, Hirsch Jan, Galietta Luis J V, Pedemonte Nicoletta, Zemans Rachel L, Dolganov Gregory, Verkman A S, Matthay Michael A
Abstract excerpt
Previous studies in intact lung suggest that CFTR may play a role in cAMP-regulated fluid transport from the distal air spaces of the lung. However, the potential contribution of different epithelial cells (alveolar epithelial type I, type II, or bronchial epithelial cells) to CFTR-regulated fluid transport is unknown. In this study we determined whether the CFTR gene is expressed in human lung alveolar...
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