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Article

CFTR channels in immortalized human airway cells

1 Dec 1992

Abstract excerpt

The cystic fibrosis (CF) gene codes for CF transmembrane regulator (CFTR), a small-conductance linear Cl- channel, but numerous studies have identified a larger conductance, rectifying Cl- channel as the adenosine 3',5'-cyclic monophosphate (cAMP)-regulated channel that is defective in airway cells. We examined Cl- conductance in a bronchial epithelial cell line that expresses CFTR, 16HBE14o-, (CFTR+) and in an...

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Identifiers

PMID: 1282304
DOI: 10.1152/ajplung.1992.263.6.l692

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