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Article

Expression and function of cystic fibrosis transmembrane conductance regulator in rat intrapulmonary arteries

27 Jun 2007

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) gene encodes a cyclic adenosine monophosphate (cAMP)-dependent chloride channel located mainly at the apical membrane of epithelial cells. In myocytes of pulmonary arteries, numerous chloride channels have been identified and described, but not the CFTR. Thus the presence and function of the CFTR was investigated in rat intrapulmonary arteries. CFTR...

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Identifiers

PMID: 17596272
DOI: 10.1183/09031936.00060007

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