Article
Mutational analysis of the DAL-1/4.1B tumour-suppressor gene locus in meningiomas.
International journal of molecular medicine - 1 Oct 2005
Martinez-Glez Victor, Bello M Josefa, Franco-Hernandez Carmen, De Campos Jose M, Isla Alberto, Vaquero Jesus, Rey Juan A
Abstract excerpt
The DAL-1/41B gene (differentially expressed in adenocarcinoma of the lung), located in the chromosome 18p11.3 region, belongs to the protein family 4.1 (membrane-associated proteins), which includes the product of the NF2 gene (merlin), and the proteins, ezrin, radixin, and moesin. DAL-1/4.1B is normally expressed at high levels in the brain, with lower levels in the kidney, intestine, and testis. DAL-1/4.1B is...
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