Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of 14-3-3 binding does not impair Protein 4.1B growth suppression.

Oncogene - 29 Apr 2004

Robb Victoria A, Li Wen, Gutmann David H

Abstract excerpt

Meningiomas are common central nervous system tumors; however, the mechanisms underlying their pathogenesis are largely unknown. Collaborative studies from our laboratory demonstrated a direct association of 14-3-3 with the meningioma tumor suppressor Protein 4.1B, which was not observed with other members of the Protein 4.1 family, including the NF2 meningioma tumor suppressor, merlin/schwannomin. Given the role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 14-3-3 Proteins
Share to Genes, Reporter
Share to Meningioma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microfilament Proteins

Share to Phenylalanine

Share to Recombinant Fusion Proteins

Share to Tumor Suppressor Proteins

Share to Tyrosine 3-Monooxygenase

Source

Identifiers

PMID: 15116094
DOI: 10.1038/sj.onc.1207445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Disruption of 14-3-3 binding does not impair Protein 4.1B growth suppression.PMID 15116094Read ↗

Mutational analysis of the DAL-1/4.1B tumour-suppressor gene locus in meningiomas.Semantic proximity Read ↗

Protein 4.1 tumor suppressors: getting a FERM grip on growth regulationSemantic proximity Read ↗

Loss of the putative tumor suppressor band 4.1B/Dal1 gene is dispensable for normal development and does not predispose to cancer.Semantic proximity Read ↗

The neurofibromatosis type 2 gene product, schwannomin, suppresses growth of NIH 3T3 cells.Semantic proximity Read ↗

Neurofibromatosis 2: loss of merlin's protective spell.Semantic proximity Read ↗

The Neurofibromatosis 2 Tumor Suppressor Gene Product, Merlin, Regulates Human Meningioma Cell Growth by Signaling through YAPSemantic proximity Read ↗

Schwannomin inhibits tumorigenesis through direct interaction with the eukaryotic initiation factor subunit c (eIF3c)Semantic proximity Read ↗

Merlin, DAL-1, and progesterone receptor expression in clinicopathologic subsets of meningioma: a correlative immunohistochemical study of 175 cases.Semantic proximity Read ↗

Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L.Semantic proximity Read ↗

Detection of cellular proteins that interact with the NF2 tumor suppressor gene product.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.