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Article

Protein 4.1 tumor suppressors: getting a FERM grip on growth regulation

1 Nov 2002

Abstract excerpt

Members of the Protein 4.1 superfamily have highly conserved FERM domains that link cell surface glycoproteins to the actin cytoskeleton. Within this large and constantly expanding superfamily, at least five subgroups have been proposed. Two of these subgroups, the ERM and prototypic Protein 4.1 molecules, include proteins that function as tumor suppressors. The ERM subgroup member merlin/schwannomin is...

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Identifiers

PMID: 12356905
DOI: 10.1242/jcs.00094

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