Article
Screening for gene mutations in a 500 kb neuroblastoma tumor suppressor candidate region in chromosome 1p; mutation and stage-specific expression in UBE4B/UFD2.
Oncogene - 17 Apr 2003
Krona Cecilia, Ejeskär Katarina, Abel Frida, Kogner Per, Bjelke Jill, Björk Elin, Sjöberg Rose-Marie, Martinsson Tommy
Abstract excerpt
Deletion of a part of the short arm of chromosome 1 is one of the most common chromosomal rearrangements observed in neuroblastoma (NBL) tumors and it is associated with a poor prognosis. No NBL tumor suppressor gene has yet been identified in the region. Our shortest region of overlap of deletio...
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