Article
Distinct expression of Survivin splice variants in breast carcinomas.
International journal of oncology - 1 Oct 2005
Vegran Frédérique, Boidot Romain, Oudin Claire, Riedinger Jean-Marc, Lizard-Nacol Sarab
Abstract excerpt
Survivin, a member of the inhibitor apoptosis family, is expressed in several human tumours, and its expression is regulated by p53. Recently, three alternative splice variants (Survivin-2B, Survivin-deltaEx3 and Survivin-3B), differing in their antiapoptotic properties, were identified. To date, little is known about the expression of all Survivin splice variants in breast cancer, particularly the recently...
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