Article
Differential expression of survivin and its splice variants, survivin-DeltaEx3 and survivin-2B, in bladder cancer.
Cancer detection and prevention - 1 Jan 2009
Atlasi Yaser, Mowla Seyed Javad, Ziaee Seyed Amir-Mohsen
Abstract excerpt
BACKGROUND: Survivin, an inhibitor of apoptosis protein (IAP), has been regarded as a valuable tumor marker for diagnosis and prognosis of bladder cancer. Recently, three splice variants of the gene with different anti-apoptotic activities have been reported. However, there is no data on the expression and potential causative roles of these transcripts in bladder cancer. Here, we have investigated the expression...
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