Article
Identification of a novel splice variant of the human anti-apoptopsis gene survivin.
Biochemical and biophysical research communications - 13 Feb 2004
Badran Adel, Yoshida Akira, Ishikawa Keiko, Goi Takanori, Yamaguchi Akio, Ueda Takanori, Inuzuka Manabu
Abstract excerpt
Survivin, a new member of the inhibitor of apoptosis protein (IAP) family, has been reported to be expressed in many cancers but not in differentiated normal tissues. In the present study, we describe the identification of a novel alternatively spliced survivin transcript, designated as survivin-3B. It comprises 5 exons including novel exon 3B derived from a 165-bp long portion of intron 3. Acquisition of a new...
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