Article
Apoptosis gene signature of Survivin and its splice variant expression in breast carcinoma.
Endocrine-related cancer - 1 Dec 2011
Végran Frédérique, Boidot Romain, Bonnetain Franck, Cadouot Muriel, Chevrier Sandy, Lizard-Nacol Sarab
Abstract excerpt
Survivin, an anti-apoptotic protein, was described as strongly expressed in human cancers including breast cancer. However, little is known about the association between Survivin variants (Survivin-2B, Survivin-ΔEx3, Survivin-3B, and Survivin-2α) and the other apoptotic-related genes. In this study, we analyzed the apoptosis gene signature of Survivin and its variant expression in breast cancer. Human Apoptosis...
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