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Transcriptional expression analysis of survivin splice variants reveals differential expression of survivin-3α in breast cancer.

Genetic testing and molecular biomarkers - 1 Apr 2013

Moniri Javadhesari Solmaz, Gharechahi Javad, Hosseinpour Feizi Mohammad Ali, Montazeri Vahid, Halimi Monireh

Abstract excerpt

Survivin, which is a novel member of the inhibitor of apoptosis family proteins, is known to play an important role in the regulation of cell cycle and apoptosis. Differential expression of survivin in tumor tissues introduces it as a new candidate molecular marker for cancer. Here we investigated the expression of survivin and its splice variants in breast tumors, as well as normal adjacent tissues obtained from...

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Identifiers

PMID: 23368531
DOI: 10.1089/gtmb.2012.0411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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